About Conference
Conference Series LLC LTD proudly presents 6th World Congress on Parkinson’s & Huntington’s disease. We invite participants around the world to Rome, Italy for Parkinson's Congress 2020 held during September 20-21, 2020.
Parkinson's Congress deals with Neurological Syndromes caused
due to leakage of electric impulse in neurons which leads to loss of
communication. This kind of medical conditions are getting frequent in
humans at present situations. It has been observed there are number of
diseases associated with Neurological disorders for examples Parkinson’s diseases, Huntington’s, Alzheimer’s disease, brain tumours, Multiple Sclerosis, Spinal Muscular Atrophy, Brain Stroke, Epilepsy, Amyotrophic Lateral Sclerosis.
According to current survey Neurological disorders occupy first place in Europe Brain disorders are like Brain Tumour, Cerebral palsy, chiari malformation, Craniofacial abnormalities, Craniosynostosis, Developmental disorders, Encephalopathy, Epilepsy are recognized by World Health Organization in Europe. It is been identified 1.2 million people in Europe are suffering with Parkinson’s approximately 260000 people in Germany, 200000 people in Italy, 150000 people in Spain, 120000 people in UK, 117000 people in France are suffering from Parkinson's disease.
World Health Organization (WHO) and World Federation of Neurology (WFN)
were collaborated after find the rate of Neurological disorders
worldwide. An international Survey of Country Resources for Neurological disorders effects
109 countries and covering over 90% of the world’s population. This
survey helps to collect valuable information regarding aspects of
neurological care all around the world.
At National Institute of Health funding package is of $34 billion for the economic year 2017 to improve life of patients who are suffering from Parkinson’s disease and
to raise the awareness on Neurological disorders around the World. PRP
(Parkinson's Research Program) fund received amount of $16 million
annually to research in neuromuscular disorders such as Alzheimer’s, Parkinson’s disease and Huntington’s disease.Conference Highlights
Session on: Parkinson Disease
Parkinson’s disease (PD)
is a chronic and progressive disease of nervous system that possess
symptoms which continue and become worse over time. It is the second
commonest neurodegenerative disease
after Alzheimer's disease, and in the UK, has a lifetime prevalence of
between 0.1 and 0.3% of the population. The basic reason behind this
condition is malfunction and death of vital nerve cells in brain. In
normal conditions nerve cells present in the brain produces a neurotransmitter called dopamine that is responsible for signalling movement, emotions and co-ordination but in the case of diseased individual dopamine production
slows down, hence the individual become unable to control the movement
normally. There is no cure but treatment involves medication and
surgery. Slowness of voluntary movements, reduced facial appearance,
repetitious tongue, and diminished eye flashing, A shuffling gait with
deprived arm swing and curved posture, Shaky stability; difficulty
rising from a sitting position, Swallowing problems in later stages.
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Associations:
National Parkinson’s Foundation, European Parkinson’s Disease Association, American Parkinson’s Disease Association, UK Parkinson’s Action Network, American Academy of Neurology, Movement Disorders Society, European Neurological Society, Parkinson’s Society Canada, Michael J. Fox Foundation, Parkinson’s Association of the Carolinas, Parkinson’s NSW, Parkinson's Unity Walk, Movement Disorder Society of Japan, Austrian Parkinson's Disease Society, International Parkinson’s and Movement Disorder Society, Danish Movement Disorder Society
Session on: Epidemiology of Parkinson’s
Parkinson's disease is a neurodegenerative disorder and
the cause of it remained a mystery to the scientific community.
Researchers say by exposing to harmful chemicals and Pesticides
mutations occurs in the genes and results in neurological disorders.
With age, the condition of disease increases exponentially and men are
in higher proportion to prone compared to women. On an average 10million
individuals are found to be suffering from Parkinson’s disease, from where only four present of people with Parkinson’s disease are diagnosed before the age of 50. An estimated of 40% to 60% of Parkinson disease patients suffering from depression. United States stands in the fourth position in considering the death of people due to Parkinson’s disease.
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Associations:
National Parkinson’s Foundation, European Parkinson’s Disease Association, American Parkinson’s Disease Association, UK Parkinson’s Action Network, American Academy of Neurology, Movement Disorders Society, European Neurological Society, Parkinson’s Society Canada, Michael J. Fox Foundation, Parkinson’s Association of the Carolinas, Parkinson’s NSW, Parkinson's Unity Walk, Movement Disorder Society of Japan, Austrian Parkinson's Disease Society, International Parkinson’s and Movement Disorder Society, Danish Movement Disorder Society
Session on: Neuromuscular Disorders
Neurons are the specialized cells that are responsible for
communication, when they cannot produce signals communication between
nervous system breaks and results in neuromuscular disorders.
Most of these disorders are thought be inheritable and treatment is
given to improve the life of patient and no cure is available to
completely eradicate the condition.
Associations:
National Parkinson’s Foundation, European Parkinson’s Disease Association, American Parkinson’s Disease Association, UK Parkinson’s Action Network, American Academy of Neurology, Movement Disorders Society, European Neurological Society, Parkinson’s Society Canada, Michael J. Fox Foundation, Parkinson’s Association of the Carolinas, Parkinson’s NSW, Parkinson's Unity Walk, Movement Disorder Society of Japan, Austrian Parkinson's Disease Society, International Parkinson’s and Movement Disorder Society, Danish Movement Disorder Society
Session on: Huntington’s disease
Huntington’s disease is inherited from Parents and often symptoms will be more like Parkinson’s disease which include problem with mood, mental abilities, Swallowing, Speaking, Sleep Disturbances followed by loss of co-ordination and unsteady gait. A gene called HTT(Huntingtin) which is responsible for coding protein Huntingtin, if any mutation to that gene it will cause disturbances in the brain and results in death of brain cell and leads to Huntington’s disease.
Abnormalities with the mutant huntingtin include Cardiac Failure,
Weight Loss, Osteoporosis, reduced glucose level. This condition is
normally observed in the individuals under the age of fifties.
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Associations:
National Parkinson’s Foundation, European Parkinson’s Disease Association, American Parkinson’s Disease Association, UK Parkinson’s Action Network, American Academy of Neurology, Movement Disorders Society, European Neurological Society, Parkinson’s Society Canada, Michael J. Fox Foundation, Parkinson’s Association of the Carolinas, Parkinson’s NSW, Parkinson's Unity Walk, Movement Disorder Society of Japan, Austrian Parkinson's Disease Society, International Parkinson’s and Movement Disorder Society, Danish Movement Disorder Society
Session on: Risk Factors of Parkinson’s disease
Symptoms and progression of disease will not be similar among the
suffering individuals but people with Parkinson’s are at higher rate of
developing related risks. Developing these conditions is not a
certainty, only a possibility. Knowing the conditions can help a person
with Parkinson’s disease or associated symptoms and helps to take preventative measures for a better life. Parkinson’s disease has a chance of creating mental ailment which can be mild or serious. It includes cognition (early
stage symptoms), mood, and behaviour which are considered as major
impairment when compared to normal population. The common mood
alterations seen in the patients are despair, eagerness, indifference.
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Associations:
National Parkinson’s Foundation, European Parkinson’s Disease Association, American Parkinson’s Disease Association, UK Parkinson’s Action Network, American Academy of Neurology, Movement Disorders Society, European Neurological Society, Parkinson’s Society Canada, Michael J. Fox Foundation, Parkinson’s Association of the Carolinas, Parkinson’s NSW, Parkinson's Unity Walk, Movement Disorder Society of Japan, Austrian Parkinson's Disease Society, International Parkinson’s and Movement Disorder Society, Danish Movement Disorder Society
Session on: Pathophysiology and Pharmacology
Parkinson’s disease is originated because of the gradual loss of cells in the substantia nigra of the brain. Dopamine is a neurotransmitter that transmits signals between two regions of the brain to coordinate activities like movement of limbs. If there is deficiency in dopamine production results in loss of co-ordination and end up with symptoms of Parkinson’s disease. As the disease progresses, nervous system and brain degenerates causing a higher movement disorder.
Associations:
National Parkinson’s Foundation, European Parkinson’s Disease Association, American Parkinson’s Disease Association, UK Parkinson’s Action Network, American Academy of Neurology, Movement Disorders Society, European Neurological Society, Parkinson’s Society Canada, Michael J. Fox Foundation, Parkinson’s Association of the Carolinas, Parkinson’s NSW, Parkinson's Unity Walk, Movement Disorder Society of Japan, Austrian Parkinson's Disease Society, International Parkinson’s and Movement Disorder Society, Danish Movement Disorder Society
Session on: Diagnosis for Parkinson’s disease
Early stage identification of Parkinson’s disease is
difficult but includes some imaging studies. MRI (magnetic resonance
imaging) and CT (computer tomogram) are used by many physicians to find
out other relating Parkinson’s diseases such as encephalitis, Tumours, Hydrocephalus. Level of dopamine release and activity of brain can easily detect using PET and SPECT examining.
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Associations:
National Parkinson’s Foundation, European Parkinson’s Disease Association, American Parkinson’s Disease Association, UK Parkinson’s Action Network, American Academy of Neurology, Movement Disorders Society, European Neurological Society, Parkinson’s Society Canada, Michael J. Fox Foundation, Parkinson’s Association of the Carolinas, Parkinson’s NSW, Parkinson's Unity Walk, Movement Disorder Society of Japan, Austrian Parkinson's Disease Society, International Parkinson’s and Movement Disorder Society, Danish Movement Disorder Society.
Session on: Parkinson’s disease: Complications
Parkinson's disease is usually accompanied by additional problems, which may be cured and they are thinking difficulties, swallowing problems, depression and emotional changes, sleep difficulties, constipation, blood pressure changes, fatigue, pain.
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Associations:
National Parkinson’s Foundation, European Parkinson’s Disease Association, American Parkinson’s Disease Association, UK Parkinson’s Action Network, American Academy of Neurology, Movement Disorders Society, European Neurological Society, Parkinson’s Society Canada, Michael J. Fox Foundation, Parkinson’s Association of the Carolinas, Parkinson’s NSW, Parkinson's Unity Walk, Movement Disorder Society of Japan, Austrian Parkinson's Disease Society, International Parkinson’s and Movement Disorder Society, Danish Movement Disorder Society
Session on: Mitochondrial Dysfunction
The known cause of Parkinson’s disease is reduced level of dopamine production
by neurons in the brain but surprisingly the main cause was
malfunctioning of cell organelles like mitochondria leads to increased
oxidative stress which in turn results in cell death and finally ends
with Parkinson’s disease with motor and non-motor symptoms. The reason may be both genetic and environment factors.
Associations:
National Parkinson’s Foundation, European Parkinson’s Disease Association, American Parkinson’s Disease Association, UK Parkinson’s Action Network, American Academy of Neurology, Movement Disorders Society, European Neurological Society, Parkinson’s Society Canada, Michael J. Fox Foundation, Parkinson’s Association of the Carolinas, Parkinson’s NSW, Parkinson's Unity Walk, Movement Disorder Society of Japan, Austrian Parkinson's Disease Society, International Parkinson’s and Movement Disorder Society, Danish Movement Disorder Society
Session on: Insights and therapeutics: Parkinson’s disease
No cure has been identified to Parkinson’s disease,
but use of drugs can slow down the progression. Normally prescribed by
physicians include change of life style, regular aerobic exercise and
prescribed therapeutic supplement. It is noted that people will have
beneficial effect who are taking co-enzyme Q10 during their initial
stage of disease. It is unclear how genetically changes cause Parkinson
disease or influence the risk of developing the disorder. Some gene
mutations(alterations) such as LRRK 2, PARK 7, PINK 1, PRKN disturb the
cell mechanism that breaks down undesired proteins in neurons which are
responsible for dopamine production.
Hence, under graded proteins accumulate, resulting in death of vital
nerve cells and subsequently lowers the level of dopamine production. In
most cases of Parkinson disease, protein deposits called Lewy bodies.
It is unclear whether Lewy bodies play a key role in killing nerve
cells or just part of the cells which are responsible to the disease.
Yoga, massage, acupuncture, meditation, music or art therapy, alexander
technique is also regarding as best methods to control neurological disorders particularly Parkinson’s disease, Alzheimer’s and neuropsychiatric. Tetrabenazine, neuroleptics, mirtazapine can be taken to for treating chorea.
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Associations:
National Parkinson’s Foundation, European Parkinson’s Disease Association, American Parkinson’s Disease Association, UK Parkinson’s Action Network, American Academy of Neurology, Movement Disorders Society, European Neurological Society, Parkinson’s Society Canada, Michael J. Fox Foundation, Parkinson’s Association of the Carolinas, Parkinson’s NSW, Parkinson's Unity Walk, Movement Disorder Society of Japan, Austrian Parkinson's Disease Society, International Parkinson’s and Movement Disorder Society, Danish Movement Disorder Society
Session on: Managing life with Parkinson’s disease
Since the symptoms and progression of disease are not similar among
individuals early stage detection can help to reduce the worseness.
Treatment and complete abolition is not known to research groups but
maintaining the instructions and following the medication prescribed by
physician can better the life. Individual should get practised to
maintain the stress levels and depression by
daily communicating with close relatives, friends. Patients can improve
the life by following guidelines given by counsellor.
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Associations:
National Parkinson’s Foundation, European Parkinson’s Disease Association, American Parkinson’s Disease Association, UK Parkinson’s Action Network, American Academy of Neurology, Movement Disorders Society, European Neurological Society, Parkinson’s Society Canada, Michael J. Fox Foundation, Parkinson’s Association of the Carolinas, Parkinson’s NSW, Parkinson's Unity Walk, Movement Disorder Society of Japan, Austrian Parkinson's Disease Society, International Parkinson’s and Movement Disorder Society, Danish Movement Disorder Society
Session on: Neurosurgery
Presently Deep brain stimulation is widely recommended for improving people suffering with Parkinson’s disease one
is deep brain stimulation (DBS) and is performed by inserting a tube in
the small intestine and is used to treat a variety of deactivating neurological symptoms most commonly the draining symptoms of Parkinson’s disease (PD),
such as tremor, rigidity, stiffness, slowed movement, and walking
problems. There will be no effect with using DBS to healthy brain tissue
by terminating nerve cells. Instead the procedure blocks electrical
signals from targeted areas in the brain.
Associations:
National Parkinson’s Foundation, European Parkinson’s Disease Association, American Parkinson’s Disease Association, UK Parkinson’s Action Network, American Academy of Neurology, Movement Disorders Society, European Neurological Society, Parkinson’s Society Canada, Michael J. Fox Foundation, Parkinson’s Association of the Carolinas, Parkinson’s NSW, Parkinson's Unity Walk, Movement Disorder Society of Japan, Austrian Parkinson's Disease Society, International Parkinson’s and Movement Disorder Society, Danish Movement Disorder Society.
Session on: Free Radicles and Aging in Parkinson’s
Free radicles have both beneficial and baleful effect to human body.
These are produced with in the body by metabolism and enters body
through external sources such as pollution, radiation, therapeutics etc;
Oxidative stress is known to cause many neurological diseases such as Alzheimer’s, Parkinson’s disease, Amyotrophic lateral sclerosis(ALS). With oldness, there is a typical failure of the dopamine producing
neurons. Out of surprise 2% of the 1 million people with the disease
are thought to be below the age of fifty. In some of the rare situations
symptoms are seen in children and teens and it is known as juvenile Parkinsonism.
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Associations:
National Parkinson’s Foundation, European Parkinson’s Disease Association, American Parkinson’s Disease Association, UK Parkinson’s Action Network, American Academy of Neurology, Movement Disorders Society, European Neurological Society, Parkinson’s Society Canada, Michael J. Fox Foundation, Parkinson’s Association of the Carolinas, Parkinson’s NSW, Parkinson's Unity Walk, Movement Disorder Society of Japan, Austrian Parkinson's Disease Society, International Parkinson’s and Movement Disorder Society, Danish Movement Disorder Society.
Session on: Novel Therapeutics
The commonly used drug to treat Parkinson’s disease is Levodopa which
has higher frequency to develop motor Fluctuations and results in
L-dopa-induced dyskinesia (LID). Since the Characteristic key cause of Parkinson’s disease is reduced production level dopamine by
neurons, research studies developed a molecule called LXR (Liver X
Receptor) where it has got potential to reduce the loss of dopaminergic neurons. Researchers propose novel ideas to treat Parkinson’s disease to
reduce the risk of causing side effects, frequency of dyskinesia, to
treat cognitive disorders such as anxiety and depression.
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Associations:
National Parkinson’s Foundation, European Parkinson’s Disease Association, American Parkinson’s Disease Association, UK Parkinson’s Action Network, American Academy of Neurology, Movement Disorders Society, European Neurological Society, Parkinson’s Society Canada, Michael J. Fox Foundation, Parkinson’s Association of the Carolinas, Parkinson’s NSW, Parkinson's Unity Walk, Movement Disorder Society of Japan, Austrian Parkinson's Disease Society, International Parkinson’s and Movement Disorder Society, Danish Movement Disorder Society
Session on: Clinical Trials in Parkinson’s diseases
To develop a promising drug or treatment for Parkinson’s disease observational
study is being conducted by scientist in laboratory to provide patients
with better life. Clinical trials are performed to slowdown the
progression and reduce the symptoms.
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Associations:
National Parkinson’s Foundation, European Parkinson’s Disease Association, American Parkinson’s Disease Association, UK Parkinson’s Action Network, American Academy of Neurology, Movement Disorders Society, European Neurological Society, Parkinson’s Society Canada, Michael J. Fox Foundation, Parkinson’s Association of the Carolinas, Parkinson’s NSW, Parkinson's Unity Walk, Movement Disorder Society of Japan, Austrian Parkinson's Disease Society, International Parkinson’s and Movement Disorder Society, Danish Movement Disorder Society
Session on: Psychology of Parkinson's Patients
Parkinson's disease is frequently associated with Psychological disorders like psychotic disorders, depression, psychotic disorders, and dementia after examination of psychological disorders in Parkinson’s disease one-third of Parkinson's patients experience visual hallucinations. Mood disorder and depressive symptoms are common in Parkinson's patients.
It is clear that Parkinson's disease is associated with psychological disorders which can be treated with Chemotherapy (drugs) but according to clinical trials drugs for psychological disorders can give side effect on patient so it is vital to know about the theraptic drug used for Parkinson's psychological disorders. Dose reduction of certain anitpakinsoian drugs sometimes improve psychotic disorders, Clozapine is effective and does not worse Parkinson’s symptomsSpecial Issues
- Journal of Neurological Disorders
- Journal of Neurology & Neurophysiology
- Journal of Alzheimers Disease & Parkinsonism
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